Wednesday, 13 November 2019

Personalised Drugs

Hello beautiful people, I hope you are all doing well. I know its been a long time since I put anything up on this page, turns out second year at vet school is quite tricky and overwhelming so I've been taking each day as it comes and trying not to get too stressed, at the end of the day my mental health will always come first. I hope you are having a lovely week and I just thought I'd pop on here to talk about some things we've learnt in lectures recently which I found super interesting as I did do a post on this topic a while ago called designer drugs I believe. So here goes I'm going to explain the basics behind the drugs and hopefully some of you will be able to follow along.

So T-cells make up a big part of our immune system. At school you may have been taught about T-killer cells which we call CD8+ t-cells and then you get T-helper cells which we call CD4+. this CD business is basically a protein on the T-cells that helps to determine its character and what cells it binds to. The cells T-cells bind to have MHC proteins on them which stands for Major Histocompatibility Complex. There are two classes of these MHCI and MHCII, it is these that the t-cell receptor site recognises during an immune reaction. CD8+ binds with MHCI which is found on any nucleated cell and CD4+ binds with MHCII which is found on antigen presenting cells (note that these can also be nucleated cells).
The genes to make MHC are linked and very complex on one specific chromosome in DNA. The location differs between species. These genes also encode for antigen presentation and processing.  Some of the reasons MCH are so good is because they’re polygenic and contain several different copies of MHCI and MHCII, they’re also polymorphic so many alleles of each gene in the population so greater combinations. Each individual express diff number of MHC antigens, the specific set of MHC expressed is called “tissue type” this is used when finding matches for organ transplantation. When looking at the genetics of MHC, a haplotype is taken from each mother and father and this makes a new combination, these combinations are much like the mendelian cross squares. This makes it very rare to have a tissue type match which is why graft rejection is still such a major issue. 
Only mature t-cells express a t-cell receptor with the CD 4 or 8 protein. The recognition of peptide-MHC involves both co-receptors, the TCR and CD bind to different sites on the MHC molecule so 1 MHC to both receptors, the TCR has pMHC recognition and CD4/8 enhances sensitivity. This binding isn’t dependent on a peptide being present as CD8/4 will bind without it and hence accelerate the TCR interaction with the peptide, the joining of CD8 isn’t enough to activate the t-cells are overcome the activation threshold just lower it, as MHCI doesn’t have a high enough affinity to the CD8. Once a T-cell has bound the two receptors onto the MHC then signals start to cascade which causes cytokines to be released which effectively kill the harmful pathogen in the body. 

The different type of T-helper cells. TH1 activates macrophages to kill intracell organisms and stimulated CD8 t-cells. TH2, helps B-cells differentiate to plasma cells to secrete Ab’s (antibodies). TH17 recruits’ neutrophils to infection sites. Remember CD4 are T-helper cells. The immune response can be polarized towards Th1 or Th2 which is called immune deviation. Each are mutually antagonistic and depend on the CD4 which is triggered. Th1 cells produce IFN (interferon) gamma which inhibits Th2 (cytotoxic cell mediated immunity. Th2 cells make IL-4 and IL-13 which inhibit Th1 cells this is humoral immunity (soluble antibody immunity). Incorrect deviation is thought to contribute to pathology e.g. a dog with leishmaniosis requires a strong Th1 polarization in order to control this protozoal infection. Failure leads to chronic multisystemic disease and death. 

All CD4 t-cells arise from common precursor, the wat antigen interacts with APCs determines cytokine prod by APCs. It is a variation of 3 signals that causes different effector functions of CD4 t-cells. 
Okay so there is some of the science, now I'm going to try and explain.When presented with an antigen initially you get natural antigens then you get in day 2-7 the T-independent antibody and finally 5-12 day you get the T-dependent antibody, this is the adaptive immune response and is slower to get going. As antigen conc decrease and the immune response matures and there is more of a selection for high affinity BCR (b-cell receptor) compared to low affinity BCRs. So only responses with high affinity BCRs have a response that persists.  
Monoclonal antibodies can be used for allergy test, therapeutic monoclonals like the treatment of cancer or blocking a viral infection. Monoclonal antibodies are made by injecting a mouse with an antigen, the mouse responds to numerous determinants and activates B-cells of the different epitopes. The spleen is then removed from the mouse, which contains some antigen-specific B-cells and not antigen-specific. They then get the myeloma (plasma cell) cell line ‘immortal’ as neoplastic so they will grow continuously in cell culture.  Then the spleen B-cells are mixed with the myeloma cells, PEG is added which causes cell fusion and the fusion allows the exchange of nuclear material to create immortal plasma cells that produce antibodies these cells are called hybridomas. HAT is then added which unfuses B-cells and they die along with any unbound myeloma cells. These are dilutes into single cell pots, then cloning happens and you get pots of monoclonal cells, these can be harvested but they’re mouse antibodies so have to be humanized or caninized.
There is also Adoptive T-cell therapy, which is a treatment used to help the immune system combat diseases like cancer and infections via viruses. T-cells are collected from a patient and grown in the lab. this increases the number of T-cells that are able to kill cancer cells or fight infections. there T-cells are given back to the patient to help the immune system fight disease. It is also called tumour infiltrating lymphocyte therapy, when injected into the tumour the t-cells help the body attack the diseased cells and has been described to 'melt' the tumour.
There is also a chance to develop T-cells that express cancer specific TCRs, which seems amazing, being able to produce a large amount of CD8 t-cells in a very short amount of time and increase the affinity of the TCR to the cancer cells, however in reality it is very tricky to identify a suitable MHCI restricted tumour rejection antigen, and to isolate tumour specific TCR.
There has been a huge breakthrough in checkpoint inhibitors. the T-cells within the immunosuppressive tumour microenvironment express many Co-inhibitory receptors these deliver a negative signal to the t-cells which prevents them from activating and destroying cancer cells, so monoclonal antibodies that block the inhibitory receptors have been developed and are being used to treat humans with metastatic melanomas. 

I hope you enjoyed that and you managed to follow along at least just a little bit. I am slowly getting into the swing of university and sports, I've decided to swim 2 times a week and gym 5 times a week plus sometimes trying to incorporate some gym classes. It's all a work in progress at the beginning of university this term I did really struggle with my mental health but I'm now focussing on the small positives each day. I hope you all continue to have an amazing week and just remember to smile because you never know it could make someone's day. I will post when I next feel like it, see you then! 


Wednesday, 25 September 2019

We need more Vets

Hello everyone, I hope that you are all doing well. I apologise for not posting that much this summer, I've really been spending the time working on myself and becoming a better version of myself, hopefully some day getting to be the best version of myself. At the end of this week I'm heading back up to uni, I'm really looking forward to it because I feel like this year I can really enjoy myself and do what I love, I'm not having to figure out everything like I was having to do last year.


Anyway, so today I'm addressing the fact that the veterinary profession was put on the SOL (shortage occupancy list). So obviously this isn't good and with the UK currently muddling its way through Brexit nothing is really set in stone and if anything after Brexit the numbers of vets practicing in the UK could decrease further. I looked on the SOL and here is a list of the new roles added to it this year (2019).
  • All medical practitioner roles SOC code 2211
  • All Psychologist roles SOC code 2212
  • All veterinarian roles SOC code 2216
  • All medical radiographer roles SOC code 2217
  • All occupational therapist roles SOC code 2222
  • All speech and language therapist roles SOC code 2223
  • All nursing roles SOC code 2231
  • All social worker roles SOC code 2442
  • All paramedic roles SOC code 3213
All of these roles are vital and I hope that something can be done to try and remove these occupations from the list. There have been one or two articles that I've scanned over on BVA and VetTimes, about how we can try to combat this issue. The BVA have made a statement that training more vets won't be enough to solve this issue. They came up with a statement that sets out 50 recommendations it believes will help produce an inclusive and "future-proof" workforce. One major issue is cost, the student loans and government funding does not cover the cost of delivering one year of undergraduate veterinary degree, which is around £20,000. The number of students isn't capped and the government funding for veterinary education isn't calculated per capita. So this means that if a new vet school opens then the funding doesn't increase. So the BVA are calling for the government to change this and as more vet students are taken into uni for there to be extra funding per student in an undergraduate course.
Dr Dos Santos added: “We should look at the bigger picture and address issues at multiple points in the journey to becoming part of the veterinary workforce, including those that present after graduation.

“From widening participation schemes, communication of the diverse range of veterinary careers to the implementation of post-study work visas, there are many ways in which the BVA and other stakeholders can help maintain a gold standard while making sure we create a workforce that is capable, resilient and inclusive.”
If you would like to read the full article, it's n the vet times news page. I believe that this is and will continue to be a major issue for the veterinary profession in the UK until Brexit has gone through and the government has stabilised again. It would be nice to see extra funding for all medical degrees, we need more doctors, vets, therapists and so on but if there isn't the funding and support set up then these jobs will remain on the list. For me this issue is a big deal however once I graduate I want to relocate to Canada, it's a dream of mine that I will make a reality and I'm doing everything in my power to make happen. #
I hope you have enjoyed reading this and it has been insightful, I am going to aim to write a post every two weeks once I'm back at uni. I hope you all continue to has amazing weeks, remember to smile because you never know it could make someone's day :)

Wednesday, 28 August 2019

BIG CHANGES

Hello lovely people I hope that you are all well and have all just had a wonderful long bank holiday weekend. On Sunday morning I returned from one of the most incredible weeks in Croatia. Now as you know I've done a few posts on mental health on this blog and a few recently and I am really trying to make the change in my life to improve my mental health. So here goes.

I had the most amazing week away, I travelled by myself and it was such a freeing experience I had no one else to worry about and it was so nice for myself to be my only priority as this is very rarely the case. I spent the whole week doing absolutely nothing which is you have read any of my post you will know is an absolute miracle. I felt so happy and so content. Yes I had my good and my bad days however I spent time during my week away to listen to the Chimp Paradox (audiobook). This is a truly wonderful book and helps you to understand you mind and the reasons behind how it works and why sometimes you can almost wake up and think why was I feeling that or behaving like that. I  think that in order for me to put this book to practice I will have to listen to it again and make more notes however it was a very useful book to listen to.

This year at uni I have also planned to make some big changes. First off NO ROWING, I did enjoy it this past year however I feel like it will be best for my mental health if I didn't continue. I still love the gym and keeping fit but now instead of competing my sights are set on helping others love what they do as well. So this year I am taking a swim teacher training course so that I can coach swimming which has been and will always be my first love and I'm so glad to be going back to it. If you read back in a previous blog I believe I explained all of the way I believe that swimming and sport helped shape the person I am today and I'd love to be able to help younger kids find a love for the sport. I am also hoping to take my pt level 2 certificate. This will allow me to potentially coach classes at the gym at uni and I'm hoping to start a HIIT circuit class for some of the girls on my course and grow it from there, I'll also have the possibility of taking some classes at the gym I go to at home during the holidays which will be so amazing to be able to be in a place I love so much and be able to be helping others. I have also promised myself 1 rest day a week I believe that this will help me to achieve my goals, with rowing there were no rest days and so I had it in my mind that this was the right way to go about it and to constantly train but I realise now that it is not. Now that I'll also have weekends I'll be able to relax and spend time going to see friends and also doing some work! I can't wait for this year and all it is going to bring to the table I want to develop myself as a coach and a student and a friend. I know that this year I have become cut off and very destructive in my mindset towards myself however this year I am going to do everything in my power to change this, I do admit that I need help as I've realised I can't fix everything by myself and learning to accept help from others is going to be good for me, I know I don't have to constantly be pleasing other and that I can do things for me that make me happy without answering to other people.

In other news I have a new puppy, now as a family we didn't want to buy a puppy we wanted to adopt preferably a GSP from Serbia however due to my parents working hours this became a near impossible task despite having owned a GSP for 17 years! So everyone welcome Luna into the family she's a little whippet 13 weeks old and she sleeps most of the day with the occasional crazy 30 mins, she's already established herself as a sofa dog but we adore her and just pray that training continues to go well.
I hope that you all have a wonderful rest of your week and don't forget to count your blessings and smile at others because you never know it could make their day.

Sunday, 4 August 2019

Things I learnt at the Dairy

Hello lovely people I hope that you are all well and enjoying life right now wherever it's at. I have finally finished my placements for the summer which is such a relief, the final two weeks I spent on a dairy farm. I didn't manage to blog last week as I've just worked 13 days on the trot so this took a back seat. I just wanted to summarise on here what I learnt whilst I was at the dairy and the answers to some of the questions I asked the farmer.

  1. Cows are big and though 9/10 won't hurt you, it is scary when they run towards you and you have to make yourself look scary enough to make them change direction. This is something I still need to work on. 
  2. In the feed they have oats cut up for energy, soya and rape cut up and mixed for protein and then chopped straw for fibre but only if the silage that is being fed at the time is low in fibre. This all mixed together is called a ration, the cows also get cake in the parlour and depending on cows body condition at the time of year they are given salts and minerals. 
  3. I was of the belief that a high or low yield cow was just how much milk they produced and that was the same every year and stayed consistent. However I learnt that after a cow gives birth that's when they are high yield, then like a curve they start to produces less and when they are back in calf it continues to decrease and half way through pregnancy they will move to low yield. This is important because they get fed differently depending on where they are in the calving cycle. This is all automated by the collars the cows wear that tells the computer system how much the cow is producing then the sorting gate after milking puts the cows in different holding pens. 
  4. One of my questions was; How do you introduce heifers into the main herd? I asked this because during our lectures on cows this year I remember a big emphasis being put on this and how it can be stressful for heifers. The answer was not as much as what we learnt about this year however the farmer did say that after she had calved they get moved to the back shed and the calf is taken away almost as soon as it's had colostrum, in this shed she can hear the other cows coming in for milking and hear the noises of the parlour just and initially she is only milked once a day. They have all been in cubicles before and so that is no issue. Also there cows aren't kept inside all year long in the spring and summer they go out on the grass all day and at night. 
  5. What is a ration? it is given in kg per cow, the nutritionist will assume the amount eaten when grazing, then give the amount for silage and maze, after this they add in all the other bits as above and they equates to overall dry matter per cow and cost. That's normally only fed as an extra to the high yield cows as they need the extra energy to produce milk. 
  6. The difference between costing and benchmarking; costings= efficiency of farm no profit and benchmarking= comparing to other contemporaries based off factors. The reason it's hard to benchmark is because margin over purchased feed to compare which is normal depends on how much they grow, and some do a lot of grazing so margin per litre is higher as they don't have to buy in food, which is also why calving in spring time is more profitable. 
  7. This farm was aiming for more autumn calving I believe, and so from what I understood the average days in milk increases meaning that more stale cows peak in December and January meaning that now there's been a drop in litre per cow per day, so mixer needs to be added to food and more buffer to prevent the litres per cow per day from dropping. 
  8. When getting a heifer into calf for the first time you want to try and make sure that she calves at the beginning of the desired window of calving because each calving is just over a year ( the cycle) so by the 4th calf she'll still be in the desired window. This farm were aiming for autumn calving because the wanted better live weight sooner with calves which is easier to achieve when they are kept in a barn over winter. 
  9. Farmers are sometimes difficult to understand however once you get the hang of it you start to understand their otherwise foreign language. 
  10. It takes a whole lot of people and time to cover a load of crop in a silage press, it's very hot and humid on a silage press and so many layers go into the covering. 

So there it is what I learnt in my two weeks on a dairy farm, oh also it goes without saying the hours are stupidly long and the guys that work there are going 24:7 caring for the animals. I really enjoyed the placement however I am glad that I can now say it is over with and I can enjoy my summer a bit more. I hope you enjoyed reading that and I hope you have a wonderful week don't forget to smile at people because you never know it could make their day :)   

Sunday, 21 July 2019

Mental Health

Hello everyone I hope that you have all had an amazing week, I thought I'd just come on here today and just talk through some things I've realised this week and just what I am going through at the moment. I'm not doing this as a pity thing more as a hope to help other people maybe going through the same thing so that they realise they aren't alone.

So I am now 4 weeks through my 6 weeks of placement for this summer. This week I was at the stables again and I feel like I helped a lot of kids this week with learning to ride and I took a bit more initiative when doing jobs around the yard. This week I also helped to explain what it takes to get into vet school to a 13 y/o who said she wanted to be a vet. I think that some people really don't realise what it takes but the thought that I could help this girl was lovely and I wish her all the best with getting into uni. Also this week I've been reflecting on my year out, I think it was the best thing that could have happened to me at that point in my life. In my year out I worked and saved a lot of money, went on some amazing holidays and really grew as a person and matured into a more rounded person which helped me so much when I got to uni. So if you are faced with the prospect of taking a year out whether by choice or due to exam results or sickness, think of it as an opportunity to enjoy yourself and get some savings for when you get to uni.

Now onto the mental health topic. I think that this is such an important topic to talk about. In the past I have struggled with mental health and still to this day I have good and bad days. Recently due to the stress of uni and the rest of my life I broke up with my long term boyfriend, now this was a really hard thing for me to do because though it may sound weird I didn't want it to happen, I sort of fell out of love due to where I am mentally right now and where my life is at. Luckily we are both still good friends and talk every day which is a great help to me because I think he is an incredible person and I'm so lucky that he understands where my head is at right now and can support me through this.

I always knew that university was going to be hard, I have a tendency to put a lot of pressure on myself and be very harsh to myself all the time, so along with all of the sport that I do and the university hours it can all build up and be very overwhelming from time to time. This is where my issue comes in. I can't stop. This is something I've always struggled with, people will often just say to me my parents included well you don't have to do all the things you do. In my head it's a different story, I tell myself that I constantly need to be working hard in the gym, in the library and on my diet and my body. The thought of stopping scares me because if something goes wrong because I stopped and chilled then it's my fault and only my fault. I don't know how I am ever going to change this mentality and probably at university next year I will go to the mental health service and try to get some help, I'm just worried they'll say what everyone else has always said. Deep down I don't know if I want to change because I am proud of my work ethic and what its got me in life however I know that I won't be able to continue like this forever. Internally is like a constant battle to keep going and keep being better and improving when I know that I just need to be happy with where I am right now.

Secondly my body image, I have a fitness Instagram which I post on regularly (@simply_fit_sam) I am proud of it and I push myself bloody hard in the gym to try and better myself, by training 9 times a week even in holidays. However even though I do this, every time I look in the mirror I don't like what I see, my stomach isn't flat enough, my legs have too much fat and not enough muscle, all I see is my imperfections. I have quite a few dresses that I brought with friends and don't have the confidence to pull out of my wardrobe and wear because you can see my tummy fat in them. Mentally its a struggle because I want to be able to love myself and I think that that is one of the reasons my relationship fell apart because I currently don't have the ability to love myself, which I am working on. I have always been the girl who doesn't give a F what anyone thinks of her, I will do what I believe to be right and so people can think what they want but that doesn't phase me however I am my own worse critic, in my head there will quite often be things going around in there that aren't true but it is the way I perceive myself though I wish I didn't. I am working on changing this and I know that this is something I am going to have to work on everyday and will take a long time but I have to do this myself no one else can do it for me and when I am able to stand there and say I love myself then and only then do I feel like I'll truly be happy and able to love another person with all my heart.

If you are reading this and you relate to any of these issues feel free to comment or dm me on insta I'd love to hear from you and give you words of encouragement. I think that talking about things like this really helps move past it and I hope that one day I'll be able to come on here and say that I found self love, but until then I'll keep you updated.

I hope you have enjoyed reading this and that you are all well and have had a wonderful weekend. Just remember this week if you feel down try to smile at someone because it'll make you feel better and you never know it could make someone else's day :)  

Saturday, 13 July 2019

Adulting

Hello lovely people I hope that you are all doing well and loving the summer. So I am now 3 weeks into the 6 weeks of placement I have this summer. I cannot wait to finish I'm not going to lie, I feel like when I finish I'll be able to enjoy my summer and relax more. At the moment I am having to look after the house for two weeks while everyone in my family is away in Europe. I'm just going to go over some things that I've learnt over my placement weeks so far and how I'm finding having to be an adult.

So I know they say that when you turn 18 you are an adult and in some sense of it yes you are but I feel like it's only in writing, looking after the whole house and garden by myself these two weeks has been an eye opening experience. Every morning getting up I can't just go and eat my breakfast get dressed and leave the house there is a whole list of jobs that I need to do before leaving for an 8:30-5:30 working day. These include doing the watering, opening up the greenhouse, letting the chickens out and feeding them along with opening up the curtains in the house and tidying the kitchen and putting on the alarm before leaving. Now I realised before that all of this had to be done however when you are the sole person in charge of doing this then it really does show how much there is to do. Adulting is tough, trying to manage all the food in the fridge is hard, I find it easy at uni because I am in full control of the buying but at home I'm not so I'm having to try and stay on top of everything. Also picking all of the vegetables in the garden, let me tell you vegetables grow bloody fast! I'm having to give away eggs and veg because I can't eat all of it! I think if this was all I was having to do I'd be okay but the fact that I'm having to do an adult job doing full days and trying to stay on top of my 9 gym session a week. It is a lot. I think it makes me appreciate my parents a lot more and shows how well they work as a team.

So this week I've been working at a stable. The days have been long and in the first week alone I've managed to walk 125 km, I also was able to get back on a horse and ride this week which felt amazing though my legs haven't been thanking me for that. I'd say that some things I've learnt about horses this week are that they constantly need mucking out or need to be given hay and that when dealing with horses that are being rude you have to tell them they are being rude an stand up for yourself so that they know they can't mess with you. I've also been able to lead horses in lessons which holds a sense of responsibility because you are having to control the horse for the rider and to give the rider tips about what they can be doing better. I have one week left at the stables and in that week I would like to improve my confidence with taking horses out to the fields, picking out back feet and my own riding skill.

I hope that you have enjoyed reading this I'm hoping that next week once I'm off adulting duty I'll be able to do a more informative blog post, I hope that you all have an amazing week and just remember to smile because you never know it could make someones day :)

Sunday, 30 June 2019

Where do our dogs go when we are on holiday?



Hello lovely people, I hope that you are all having a wonderful time in the sun in the UK or wherever you are in the world. As a side note in this heat please ensure that you are looking after your dogs appropriately, so please don’t walk them in the middle of the day when it is hottest, also please be careful when walking them on roads because the hot tarmac can burn their pads, make sure that water is always provided and that they have somewhere they can lie indoors that is cool so that they don’t overheat.

On with the blog, having started my 6 weeks of placement this week with 2 weeks at a kennels I got to thinking about when we go on holiday what are the options for caring for our dogs and which I think are the best?

I would say that the options you have are boarding kennels, house boarding, staying with family or house sitting. I’m going to outline what I thin are the positives and negatives of each one and which one I think I would send my dog to plus some tips on picking which is best for your dog.

Boarding Kennels; these are kennels that house a large number of dogs, from my experience they are very noisy and the time that the dogs are walked for is a lot less than I would think fair, but it’s understandable considering the number of dogs that these kennels have to look after. I would say that if your dog/dogs are very laid back and can be walked off lead then this could be a good option for you, I think the dogs most suited to this type of kennels would be ones that are easy to care for so a simple diet and very few extra needs. I believe that these type of kennels can be the cheaper ones from the other kennel forms. My advise would be if you are thinking of sending your dog here would be to go check it out beforehand and ask as many questions as you like to ensure you are comfortable with sending your dog there.

House Kennels; I didn’t really know what to call this one but what I class this as is someone who will look after up to say 6-7 dogs at a time, the dogs get longer walks and often stay at the persons house. We sent our dog to one of these for quite a few years and she seemed to enjoy it, the dogs get longer walks and often do get constant companionship from the person running the service. I know for our dog we had to take her for a test to make sure that she was compatible with the ladies dogs and it all seemed to work very well. Another type of this would be another kennel we sent our dog to which kept quiet a few dogs however instead of spending most of the time inside they get to spend a lot of time outside running free in a field which I think is great because they don’t have a decreased activity load then. I would say that these kennels are best suited for dogs who like company and a more homely vibe, especially if they get stressed easily. It would also be good if your dog had more complicated feeding issues or care issues. I would say that they can be more expensive just because the dogs are getting better treatment with more human contact time.

Family; I believe that this is always the best option, often the dog will already know their house and the people plus if the family member has a dog then your dog will have company, often this is free and all it cost is a nice present from wherever you are visiting. In this situation the family can fully cater to all of your dogs needs and their walking times which really benefits the dog because it doesn’t put them out of their routine. We always used to send my dog to my grannies when we could because she grew up there as a puppy and she knew the house so it didn’t stress her out when we left her there. A great alternative to this would be a close friend who you live near who would put up your dog.

House Sitting; Now in the past I have done my fair share of house sitting, I know personally I am quite relaxed about what I get paid, lowest ever was £16 a day for 2 dogs and 3 ponies and highest was £40 for 3 dogs, 2 horses, chickens and sheep. I think this is a great option if you have the money, it can be more expensive depending on who you get, but at the same time you can relax in the knowledge that your house is being checked multiple times everyday and the dogs are being fed and walked in a familiar place every day. One important thing with this is to really trust and know the person who you are giving your keys over to. I pride myself in being a very sensible person who is reliable and will do the job properly. That’s just my one tip for house sitting.

I hope you have enjoyed reading this blog post I think this topic is really something to consider because you don’t want your dog to associate you going away with negative or aggressive feelings. You want it to be a holiday for them as much as it is for you. Thank you for reading I hope you all have a wonderful week and just remember to smile because you never know it could make someone’s day. P.S. I PASSED MY FIST YEAR AT UNI !